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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: SEC24C All Species: 41.21
Human Site: S888 Identified Species: 64.76
UniProt: P53992 Number Species: 14
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens P53992 NP_004913.2 1094 118325 S888 C Y R K N C A S P S S A G Q L
Chimpanzee Pan troglodytes XP_001145058 1094 118246 S888 C Y R K N C A S P S S A G Q L
Rhesus Macaque Macaca mulatta XP_001104565 998 107625 V801 L N S P V K A V R D T L I T Q
Dog Lupus familis XP_850963 1096 118584 S890 C Y R K N C A S P S S A G Q L
Cat Felis silvestris
Mouse Mus musculus Q3U2P1 1090 118764 S881 A Y R S S V L S G Q Q P G L M
Rat Rattus norvegicus NP_001102926 1095 118506 S889 C Y R K N C A S P S S A G Q L
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001513100 1030 112379 L833 I Y L F Q L I L P D A M K V L
Chicken Gallus gallus XP_421617 1147 124543 S941 C Y R K N C A S P S S A G Q L
Frog Xenopus laevis NP_001087832 1126 123503 S920 C Y R K N C A S P S S A G Q L
Zebra Danio Brachydanio rerio XP_700597 1315 142554 S1111 C Y R K N C A S P S S A G Q L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera XP_392952 1276 140829 S1069 A Y R K H C A S P S N A G Q L
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_783728 1150 123558 T944 C Y R K N C A T P S S H G Q L
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana Q9M081 1080 116273 T875 A Y R K F C A T V T S S G Q L
Baker's Yeast Sacchar. cerevisiae P53953 876 98925 L679 G L S K H I A L R P G V V P S
Red Bread Mold Neurospora crassa Q7S4P3 950 103512 G753 G L P A L C L G L T K H V G L
Conservation
Percent
Protein Identity: 100 99.5 86.9 94.8 N.A. 26.9 92 N.A. 51.9 75.4 69 59.5 N.A. N.A. 44.5 N.A. 52.6
Protein Similarity: 100 99.7 87.9 96.1 N.A. 45.8 94.4 N.A. 66.2 82.3 78.1 69 N.A. N.A. 59.4 N.A. 64.3
P-Site Identity: 100 100 6.6 100 N.A. 26.6 100 N.A. 20 100 100 100 N.A. N.A. 80 N.A. 86.6
P-Site Similarity: 100 100 13.3 100 N.A. 40 100 N.A. 26.6 100 100 100 N.A. N.A. 93.3 N.A. 93.3
Percent
Protein Identity: N.A. N.A. N.A. 33 22.4 30
Protein Similarity: N.A. N.A. N.A. 49.3 41.1 47
P-Site Identity: N.A. N.A. N.A. 60 13.3 13.3
P-Site Similarity: N.A. N.A. N.A. 80 20 20
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 20 0 0 7 0 0 80 0 0 0 7 54 0 0 0 % A
% Cys: 54 0 0 0 0 74 0 0 0 0 0 0 0 0 0 % C
% Asp: 0 0 0 0 0 0 0 0 0 14 0 0 0 0 0 % D
% Glu: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % E
% Phe: 0 0 0 7 7 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 14 0 0 0 0 0 0 7 7 0 7 0 74 7 0 % G
% His: 0 0 0 0 14 0 0 0 0 0 0 14 0 0 0 % H
% Ile: 7 0 0 0 0 7 7 0 0 0 0 0 7 0 0 % I
% Lys: 0 0 0 74 0 7 0 0 0 0 7 0 7 0 0 % K
% Leu: 7 14 7 0 7 7 14 14 7 0 0 7 0 7 80 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 7 0 0 7 % M
% Asn: 0 7 0 0 54 0 0 0 0 0 7 0 0 0 0 % N
% Pro: 0 0 7 7 0 0 0 0 67 7 0 7 0 7 0 % P
% Gln: 0 0 0 0 7 0 0 0 0 7 7 0 0 67 7 % Q
% Arg: 0 0 74 0 0 0 0 0 14 0 0 0 0 0 0 % R
% Ser: 0 0 14 7 7 0 0 60 0 60 60 7 0 0 7 % S
% Thr: 0 0 0 0 0 0 0 14 0 14 7 0 0 7 0 % T
% Val: 0 0 0 0 7 7 0 7 7 0 0 7 14 7 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 80 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _